Fabrizio was a servant at Palazzo Medici. Fabrizio's father served at table for Piero de' Medici and Carlo de' Medici.

Shortly after the female Medicis managed to retreat into Palazzo Medici during the Pazzi Conspiracy, Clarice Orsini entrusted Fabrizio with a bottle of poison, so that he would painlessly kill the children if the Pazzi and the mob managed to break into the Palazzo. As the people discovered Lorenzo de' Medici was still alive, they sided with the Medicis, and Fabrizio never had to use the poison.

Shortly afterwards, he introduced Carlo de' Medici, who had been travelling many years as a missionary, to Clarice.

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